|
|
(R)-pantoate + NADP+ <=> H+ + ketopantoate + NADPH
|
1.1.1.169
2-dehydropantoate 2-reductase
1.1.1.86
ketol-acid reductoisomerase (NADP+)
|
–
–
|
BMK
|
| |
BRENDA:
BR29231;
BS187414;
BS434963
KEGG:
R02472
MetaCyc:
2-DEHYDROPANTOATE-REDUCT-RXN
SABIO-RK:
2405
|
|
|
|
ketopantoate <=> formaldehyde + 2-oxoisovalerate
|
2.1.2.11
3-methyl-2-oxobutanoate hydroxymethyltransferase
4.1.2.12
2-dehydropantoate aldolase
|
–
–
|
|
| |
BRENDA:
BR343
KEGG:
R01216
MetaCyc:
KETOPANTOALDOLASE-RXN
|
|
|
|
5,10-methylenetetrahydrofolate + 2-oxoisovalerate + H2O <=> ketopantoate + tetrahydrofolate
|
2.1.2.11
3-methyl-2-oxobutanoate hydroxymethyltransferase
|
–
|
BMK
|
| |
BRENDA:
BR43940
KEGG:
R01226
MetaCyc:
3-CH3-2-OXOBUTANOATE-OH-CH3-XFER-RXN
SABIO-RK:
1455
|
|
|
|
ketopantoate + 3''-NADPH <=> (R)-pantoate + 3''-NADP+
|
1.1.1.169
2-dehydropantoate 2-reductase
|
–
|
|
| |
BRENDA:
BS371754
SABIO-RK:
6876
|
|
|
|
ketopantoate + alpha-NADPH <=> (R)-pantoate + alpha-NADP+
|
1.1.1.169
2-dehydropantoate 2-reductase
|
–
|
|
| |
BRENDA:
BS371755
SABIO-RK:
6880
|
|
|
|
5,10-methylenetetrahydromethanopterin + 2-oxoisovalerate + H2O <=> ketopantoate + 5,6,7,8-tetrahydromethanopterin
|
2.1.2.11
3-methyl-2-oxobutanoate hydroxymethyltransferase
|
–
|
M
|
| |
MetaCyc:
RXN-15635
|
|
|
|
ketopantoate + thio-NADPH <=> (R)-pantoate + thio-NADP+
|
1.1.1.169
2-dehydropantoate 2-reductase
|
–
|
|
| |
BRENDA:
BS371757
|
|
|
|
ketopantoate + reduced_methyl_viologen <=> Pantoate + methyl_viologen
|
1.1.99.30
2-oxo-acid reductase
|
–
|
|
| |
BRENDA:
BS371721
|
|
|
|
ketopantoate + NADH <=> Pantoate + NAD+
|
1.1.1.169
2-dehydropantoate 2-reductase
|
–
|
|
| |
BRENDA:
BS187416
|
|
|
|
(R)-pantoate + NAD+ <=> ketopantoate + NADH + H+
|
1.1.1.169
2-dehydropantoate 2-reductase
|
–
|
|
| |
BRENDA:
BS434500
|
|
|
|
L-pantoic_acid + NAD+ <=> ketopantoate + NADH + H+
|
1.1.1.169
2-dehydropantoate 2-reductase
|
–
|
|
| |
BRENDA:
BS434962
|
|
|
|
ketopantoate + reduced_benzyl_viologen <=> Pantoate + Oxidized_benzyl_viologen
|
1.1.99.30
2-oxo-acid reductase
|
–
|
|
| |
BRENDA:
BS371720
|
|
|
|
Tetrahydropteroylpentaglutamate + ketopantoate <=> (6S)-5,10-methylene-5,6,7,8-tetrahydropteroylpentaglutamate + 2-oxoisovalerate + H2O
|
2.1.2.11
3-methyl-2-oxobutanoate hydroxymethyltransferase
|
–
|
|
| |
BRENDA:
BS451906
|
|
|
|
5,6,7,8-tetrahydropteroyl-Glu4 + ketopantoate <=> 5,10-methylenetetrahydropteroyltetraglutamate + 2-oxoisovalerate + H2O
|
2.1.2.11
3-methyl-2-oxobutanoate hydroxymethyltransferase
|
–
|
|
| |
BRENDA:
BS451907
|
|
|
|
tetrahydropteroylhexaglutamate + ketopantoate <=> 5,10-methylenetetrahydropteroylhexaglutamate + 2-oxoisovalerate + H2O
|
2.1.2.11
3-methyl-2-oxobutanoate hydroxymethyltransferase
|
–
|
|
| |
BRENDA:
BS451905
|
|
|
|
tetrahydropteroylheptaglutamate + ketopantoate <=> 5,10-methylenetetrahydropteroylheptaglutamate + 2-oxoisovalerate + H2O
|
2.1.2.11
3-methyl-2-oxobutanoate hydroxymethyltransferase
|
–
|
|
| |
BRENDA:
BS451904
|
|
|
|
5,6,7,8-tetrahydropteroyl-Glu2 + ketopantoate <=> 5,10-methylenetetrahydropteroyldiglutamate + 2-oxoisovalerate + H2O
|
2.1.2.11
3-methyl-2-oxobutanoate hydroxymethyltransferase
|
–
|
|
| |
BRENDA:
BS451903
|
|
|
|
tetrahydropteroyl-Glu3 + ketopantoate <=> 5,10-methylenetetrahydropteroyltriglutamate + 2-oxoisovalerate + H2O
|
2.1.2.11
3-methyl-2-oxobutanoate hydroxymethyltransferase
|
–
|
|
| |
BRENDA:
BS451908
|
|
|
|
ketopantoate + NAD+ <=> 2-oxo-4-dehydropantoate
|
1.1.1.106
pantoate 4-dehydrogenase
|
–
|
|
| |
BRENDA:
BS186979
|
|
